焦书燕，1986年10月生人，中共党员，有机化学博士。
联系电话：15838125836
电子邮件：jiaoshuyanzi@126.com
教育经历
2012.09—2015.06 四川大学化学学院攻读有机化学博士学位师从余孝其教授
主干课程：有机合成、化学前沿、化学生物学等
2009.09-2012.06 河南大学化学化工学院获得有机化学硕士学位师从徐括喜教授
主干课程：高等有机化学、波谱解析、有机合成等
2005.09-2009.07 河南大学化学化工学院理学学士学位
工作经历
2015年-至今
中原工学院 讲师
主教课程：有机化学实验，应用化学生产实习，物理化学等课程。
横向项目情况
一系列硫酸羟氯喹药物杂质的合成工艺研发
一系列磺胺多辛和磺胺嘧啶药物杂质的合成工艺研发
羟基吡啶酮氨羧化衍生物的制备与表征
非天然氨基酸及衍生物的合成工艺开发
论文情况
1. g-C3N4-modified Zr-Fc MOFs as a novel photocatalysis-self-Fenton system toward thedirect hydroxylation of benzene to phenol, RSC Advances, 2023, 13, 19140-19148.
2.A novel fluorescent probe for Hg2+ based on the conversion of dithiane to aldehyde, Chemical Research, 2023, 34, 64-70.
3.A simple and an easy-to-synthesize turn-on fluorescent probe for rapid detection of Zn2+ and its application in bioimaging, Tetrahe dron Letters, 2020, 61: 152507-152512
4. A highly selective colorimetric fluorescence probe for Cu2+ in aqueous media: the synthesis,DFT investigation and its application in living cells, Analytical Methods, 2020, 12(7): 943-950
5. Cd(II)-terpyridine-based complex as a ratiometric fluorescent probe for pyrophosphate detection in solution and as an imaging agent in living cells, Dalton Transactions, 2015, 44: 1358-1365
6. Making pyrophosphate visible: the first precipitable and real-time fluorescent sensor for pyrophosphate in aqueous solution, Analyst, 2015, 140: 174-181 7. A BINOL-based ratiometric fluorescent sensor for Zn2+and in situ generated ensemble for selective recognition of histidine in aqueous solution, Analyst, 2013, 138: 5762-5768
8. Syntheses and highly enantioselective fluorescent recognition of alpha-hydroxyl/amino carboxylic acid anions in protic solutionsSensors and Actuators B：Chemical, 2013, 177, 384-389.
9. Syntheses and highly enantioselective fluorescent recognition of alpha-aminocarboxylic acid anions using chiral oxacalix [2] arene [2] bisbinaphthes” Chirality, 2012, 24, 646-651.
10. Progress in enantioselective recognition based on chiral crownether” chinese journal of organic chemistry, 2013, 33, 280-287.
11. 手性联萘酚的多胺缀合物的合成与表征,化学研究, 2010, 21, 52-57.
基于联萘酚的手性冠醚的合成及其晶体结构,化学研究, 2011, 22, 1-4.
12. DAP-Zn(II) based BINOL fluorescent probe for detection of phosphate anions 会议论文 2013, 上海.
专业技能
Ø 成功帮助药企筛选了三套药物杂质的合成工艺路线。
Ø 近1年完成了50个有机小分子的定制合成，包括部分偶氮类染料分子。
Ø 近一年指导学生完成了一系列的活性分散染料的合成。
Ø 能熟练掌握有机相关检测技术,紫外,荧光检测仪,HPLC, 核磁共振等仪器。
